Monday, May 25, 2020

Population Of Baltimore City And Baltimore County Essay

SECTION ONE: Population Change in Baltimore City and Baltimore County For this section, examine the data sets you’ve collected for the city and county across the different years. Be sure to pay attention to the information provided in the footnotes—this will help you understand the data you are looking at. 1. What is the population of Baltimore City today? What is the population of Baltimore County today? What proportion of the US population do these populations represent? †¢ The population of Baltimore city is 621, 849 people. The population of Baltimore County today is 831,128 people. Roughly 321,418,820 people live inside the United States in the most recent census. Baltimore city represents .19% of the U.S. population. Baltimore County represents .26% of the U.S. population. 2. How have the populations of each area changed over the past 35 years? Do they hold a larger or smaller proportion of the US population? †¢ The populations have decreased over the last 35 years. They hold a smaller proportion of the US population now. 3. Consider the category â€Å"Race and Hispanic Origin† / â€Å"Race†. †¢ How has this category in the US census changed over time? i. There are more people with Hispanic origin in the United States today than ever before. †¢ Describe the changes in racial composition from 1980 to today in Baltimore City. i. There are more people of the Hispanic and Latino race in Baltimore now than in the 1980’s. The number of AfricanShow MoreRelatedThe Social And Cultural Environment Of Baltimore1719 Words   |  7 PagesThe chart shows how Baltimore economy compares to the United States, needless to say Baltimore is struggling. Unemployment rate is higher than the rest of the United States, and job growth isn’t helping to improve Baltimore’s employment rate. To dig deeper into Baltimore’s economy, the unemployment rate for black men in Baltimore is really low. It is shown that between the ages of 20 and 24 it was 37 percent in 2013, as to being 10 percent for white men in the same category. It also doesn’t helpRead MoreHealth Informatics Case Study817 Words   |  4 Pagesbetween English-speaking doctors and Spanish-speaking patients. We would like to use the Highlandtown Healthy Living Center Branch of the Baltimore Medical System as a pilot for a technology- based Medical Translation and Transcription Service. Currently, the Baltimore Medical System has five health centers that serve almost 45,000 patients in the city and county. The Highlandtown branch has interpretation services such as 13 on-site interpreters and a phone line service available in 200 languagesRead MoreCommunity Policing and Problem Solving1135 Words   |  5 Pagesand crimes that would have been considered inconceivable in the past occurring every day in today’s time. The increase in the population of the United States is also a contributing factor to this increase in crime rate increase but also the main culprit in the need for community policing. Police departments could not have increased in size at a rate equivalent to the population so community policing techniques began to be used to help multiply the manpower of local police forces. The main philosophiesRead MoreOverview and History of the Prison District of Baltimore832 Words   |  3 PagesThe Priso n District of Baltimore, Maryland, is located primarily in an unincorporated community called Townson. With a population of just under 60,000 it is the second most densely populated unincorporated county seat in the United States. The community is located just north of Baltimore City, inside the I-695 and I-83 beltway and has several major neighborhood areas. In the larger area of Townson, the per capita income is about $32,000, but almost 10% of the population is below the poverty lineRead MoreGentrification Is Masqueraded as Revitalization1817 Words   |  8 Pagesdescription of the current transformation of the inner City of Baltimore. When we look at neighborhoods such as Westport, Federal Hill, and Canton, it is evident that gentrification is on the City of Baltimore’s agenda. During the last two terms that Mayor Martin O’Mally has presided over the city, there have been many changes in administration and the population that are causing devastating effects on t he city’s blue collar residents. The Baltimore City Department of Planning=s mission statement contendsRead MoreRacial Segregation In The Baltimore City1279 Words   |  6 Pagesa surprise to visit baltimore ,because it was a very clean and green place. There were lots of trees and parks. It wanted to stay in baltimore, until I explored the outer county. I found there weren’t any bus shuttles, the houses were not managed properly , it looked dirty and most of all it smelled foul. And there are a number of people living in such poor conditions in Maryland.The contrast between the inner and the outer baltimore made me think, why is the outer baltimore more polluted than theRead MoreEssay on A Portrait of Southside Flats1991 Words   |  8 PagesThis way of life would continue until the 1980s when the steel plant was shut down. The area was absent any major employer until 1993 when the City of Pittsburgh Urban and Redevelopment Authority (URA) bought the land once occ upied by the steel factory. The land was bought by the URA with an eye towards commercial development of the area (Pittsburgh City Council). The land eventually was used to build the SouthSide Works complex. The complex officially opened in 2004 and injected new lifebloodRead MoreHomeless And Have Hiv / Aids1617 Words   |  7 PagesTo be Homeless and have HIV/AIDS in Baltimore The problem of homelessness in American has gone pretty much unsolved since the turn of the 20th century or at least since the Great Depression and lately it seems that homelessness has become a desperate cycle often repeated for some who fail to make their way back from losing everything. This is especially true, this 21st century cycle of struggling to get back on one’s feet and then getting knocked down again before gaining any permanence, of thoseRead MoreEssay Baltimore1933 Words   |  8 PagesThe beautiful city of Baltimore, Maryland, nicknamed â€Å"Charm City† is full of historical cites and landmarks. It was founded July 30, 1729, and it was named after Lord Baltimore, the first proprietary governor of the Province of Maryland1. It was founded to serve the economic needs of 18th century farmers2. The waterways in Baltimore have been a passage for ships carrying commercial cargo and new citizens since the 1600s. Baltimore became the second leading port of entr y for immigrants to the UnitedRead MoreSocial And Social Impacts Of Slavery By Fredrick Douglass997 Words   |  4 Pagesshore of Maryland and the city of Baltimore. Throughout the story Fredrick switches his settings between the plantation he grew up in â€Å"Great House Farm† in Talbot County and Baltimore. Douglass would state that he had a little more freedom in the city of Baltimore then he did at the Great House Farm. This basically results that in the urban populations, like the city of Baltimore, keep their slave-owners from preventing any form of cruelty to their slaves, since the city is a open society. When Douglass

Thursday, May 14, 2020

Margaret Sanger s Stand Up For Birth Control Rights

Imagine being a married woman in your 30’s during the beginning of the twentieth century. You are worn out from giving birth multiple times and you are desperate to know of a way to prevent yourself from having more children. This was the exact case for millions of women in the twentieth century. Women had no rights as a person, nor did they have any rights to their own bodies. In this era, the topics of sexuality, sex and birth control were all taboo subject matters and never discussed between married or unmarried couples. It wasn’t until the year of 1912 that a woman by the name of Margaret Sanger started her crusade to promote the right for women to use contraceptives to prevent unwanted pregnancies. In this essay, I will discuss what inspired Margaret Sanger to stand up for birth control rights. I will also explore the trials and legal issues that Sanger came up against. Lastly, I will talk about the victory and the difference Sanger made for women in the twentieth century. Sanger dedicated her life and career to legalizing contraceptives all across the United States. She wanted all woman to have the freedom to decide whether or not they wanted children. Margaret Louise Higgins (Sanger was her married name) was born in the year of 1879 in Corning, New York. She was sixth of eleven children and was born into an Irish-American family. Margaret knew at a very young age that she wanted to make a difference to empower women and to leave her mark on the world. Margaret wasShow MoreRelatedMargaret Sanger Essay1428 Words   |  6 PagesMargaret Sanger The early twentieth century was a turning point in American history-especially in regards to the acquisition of womens rights. While the era was considered to be prosperous and later thought to be a happy-go-lucky time, in actuality, it was a time of grave social conflict and human suffering (Parish, 110). Among those who endured much suffering were women. As Margaret Sanger found out, women, especially those who were poor, had no choice regarding pregnancy. The only wayRead MoreMargaret Sanger : A Birth Control Activist1508 Words   |  7 PagesMargaret Sanger was not only a birth control activist, she was also an author, a nurse and a sex educator and many of her influences for being an activist come from her family. Born on September 14, 1879, in Corning, New York, she was the sixth of eleven children born into a poor Roman Catholic family (Sanger 14). Her mother had various miscarriages, which Sanger believed affected her mother’s health, and was a devoted Roman C atholic who believed one should conform to the rules while her father wasRead MoreMargaret Sangers Stand Up For Birth Control Rights1325 Words   |  6 PagesImagine being a married woman in your 30’s during the beginning of the twentieth century. You are worn out from giving birth multiple times and you are desperate to know of a way to prevent yourself from having more children. This was the exact case for millions of women in the twentieth century. Women had no rights as a person, nor did they have any rights to their own bodies. In this era, the topics of sexuality, sex or birth control were all taboo subject matters and never discussed between marriedRead MoreMargaret Sanger : A Battle Between Modernism And Traditionalism1368 Words   |  6 PagesRoaring Twenties also know as a new era which was a great time for a revolution.We think of this â€Å"New Era† as a freedom for women. Now women were â€Å"breaking down the spheres of Victorian values (Zeitz). † In 1920, the powerful women s rights movement gave the women right to vote after so many years. Now they started to become more independent and had less restriction put into them.This time period gave rise to the flapper girls who smoke, drank, and had sex as they pleased.Many women became rebelsRead MoreA Speech That Made History1553 Words   |  7 PagesAmericans were beginning to gain some basic human rights, and women were very slowly starting to gain equality with men. Women were now able to get jobs, but they were still not fully in control of their own bodies. There was a lot of (was much) controversy over topics such as pre-marital sex, birth control, and abortion, and these controversies were part of what led Margaret Sanger to give her speech about the morality of birth control in the early 1920s. Sanger used many different techniques in her speechRead MoreMaking A Change : Margaret Sanger1713 Words   |  7 PagesMaking a Change: Margaret Sanger’s 1925 Speech Margaret Sanger’s, The Children’s Era, exudes knowledge on how contraceptives and birth-control will create a better world for the children. This paper conducts a Neo-Aristotelian analysis of Margaret Sanger’s 1925 speech. It contributes to rhetorical theory by advancing knowledge of how rhetors create a consensus on the use of birth-control and contraceptives. The paper proceeds first by establishing the context of the speech, which will include theRead MoreMargaret Sanger s Life And Life1272 Words   |  6 Pages Margaret Sanger was born in Corning, New York on September 14, 1879 [3] as Margaret Louise Higgins. [1] Her father, Michael Higgins, originally studied phrenology and other medical practices, but eventually moved to being a stone cutter. Her mother, Anne Higgins, was born in Ireland, and her family moved to Canada during the Potato Famine. In 1869 Michael married Anne and she went through 18 pregnancies, only 11 of which lived. [3] Margaret was th e sixth child in this long line and spent herRead MoreEugenics And Scientific Racism : Margaret Sanger1174 Words   |  5 Pages Eugenics and Scientific Racism: Margaret Sanger The study or practice of attempting to ‘improve’ the human gene pool by encouraging the reproduction of people considered to have desirable traits and discouraging or preventing the reproduction of people considered to have undesirable traits; Eugenics. In the early 20th century, Eugenics grew popular among mainstream scientists, physicians and the generalRead MoreRisky Business1206 Words   |  5 Pagesthe future for women. Some even risked and gave up their freedom to demonstrate how important it was for society to change. I believe a great example of someone who risked many things for the future of women in society was Margaret Sanger. Sanger began her journey into historical fame as a visiting nurse, someone who saw all of the pain and suffering that women went through due to the lack of birth control and the lack of acceptance of birth control in America, at that time. Jake Sachs, a truckRead More Biography of Margaret Sanger Essay5092 Words   |  21 PagesBiography of Margaret Sanger Margaret Sanger founded a movement in this country that would institute such a change in the course of our biological history that it is still debated today. Described by some as a radiant rebel, Sanger pioneered the birth control movement in the United States at a time when Victorian hypocrisy and oppression through moral standards were at their highest. Working her way up from a nurse in New Yorks poor Lower East Side to the head of the Planned Parenthood Federation

Wednesday, May 6, 2020

The Evolution Of Micro Finance - 1651 Words

CHAPTER 3: THE EVOLUTION OF MICRO FINANCE IN NIGERIA 3.0. Introduction: In this section the need for Microfinance is discussed; the emergence and development of microfinance in Nigeria is also reviewed. Finally the chapter discuss the ownership and beneficiaries of microfinance in Nigeria. 3.1. The Need for Microfinance: The unwillingness or inability of the formal financial institutions to provide financial services to the urban and rural poor, coupled with the un-sustainability of government sponsored development financial schemes contributed to the growth of private sector-led microfinance in Nigeria. Before the emergence of formal microfinance institutions, informal microfinance activities flourished all over the country. Informal microfinance is provided by traditional groups that work together for the mutual benefits of their members. These groups provide savings and credit services to their members. The informal microfinance arrangements operate under different names: ‘esusu’ among the Yorubas of Western Nigeria, ‘etoto’ for the Igbos in the East and ‘adashi’ in the North for the Hausas (CBN, 2000). The key features of these informal schemes are savings and credit components, informality of operations and higher interest rates in relation to the formal ba nking sector. The informal associations that operate traditional microfinance in various forms are found in all the rural communities in Nigeria (Otu, et al, 2003) . They also operate in the urban centers. TheShow MoreRelatedQuestions On E Procurement Adoption1648 Words   |  7 Pagesinfo records, bidding reports, material/service catalogue, delivery and payment methods, invoice, etc.). 1.2 Hardware, Software and Telecommunication Components Through decades information telecommunication and technology has grown rapidly. This evolution allows IT infrastructure to develop up to present era; cloud computing era (Laudon and Laudon, 2012). Growth of cloud computing especially SaaS (software as a service) increases promisingly (Cisco, 2014). Follows this trend many ASPs (applicationRead MoreAn Explanation of the Britishs Stuggles to Finance the War with Napoleonic France in The British Balance of Payments1087 Words   |  5 Pageswritten by Javier Cuenca Esteban, â€Å"The British balance of payments, 1772-1820: India transfers and war finance† focuses on the British ability to finance the wars with Napoleonic France. Esteban challenges the academic state of debate regarding the importance of exports on British Industrialization by pointing out that he believes without the exports from India, Britain would have struggled to finance her wars with France and may have never become the incubator of Industrialization. His a rgument comesRead MoreInnovation and Entrepreneurship in the United Arab Emirates Essay1704 Words   |  7 PagesInstitute (2010), the Khalifa Fund demonstrates from its programs that both economic and social development can be effectively realized within any organization’s vision. In order to effectively discuss why innovation has been successful for both Micro Automation and e-Home Automation International, it is imperative that we first and foremost define what innovation in its broadest definition represents. Moore (2011) offers that innovation in its entirety represents a complex construction of divergentRead MorePersonal Statement : Leadership Development Plan1158 Words   |  5 Pagesmultiple organizations and companies, I still have a long way to go for more knowledge and experience in leadership. Leaders always need to train and adjust their skills to the ongoing evolution of economics. I see myself today as a leader that still needs to develop his skills. I teach as an adjunct and work for a finance/accounting firm. In the future, I would like to establish my own firm and continue teaching students how to establish themselves so they can succeed in life and in the future. My personalRead MoreMaster of Planning/Master of Public Administration Dual De gree 1069 Words   |  5 Pagesexperience gained in the corporate world to help environmental conservation non-governmental organizations achieve their missions of sustainable development. During my 20+ years in Corporate America, primarily in information technology and mortgage finance, I procured a diverse set of skills – business and financial management, project work, operations and human resources management – that are valuable to any organization, profit-oriented or mission-based. I have managed many different types of projectsRead MoreResearch Project : Drivers, Barriers And Constraints And Then Refine The Outlook Of Small Scale Power Generation1488 Words   |  6 PagesMicrogeneration is defined as the small-scale production of heat and/or electricity from a low carbon source (45kW for heat 50kW for electricity). The range of technologies captured by this definition includes solar photovoltaics, micro-wind, micro-hydro, heat pumps, biomass, micro-combined heat and power (microCHP) and small-scale fuel cells. (Energy Act, 2004). Uptake and development of these technologies was thought to be of critical importance if the UK is to meet its carbon budgets whilst maintainingRead MoreRole of Micro Finance in Pakistan3889 Words   |  16 Pageswhich is US$ 1 per day. Micro finance is a method to alleviate poverty and empower, and raise the living standard of poor people. Micro finances are provided by the MFIs, who address the financial needs of poor people, neglected by the conventional financial institutions. Micro financial activities are as old as 200 B.C, which were started in India in shape of moneylenders, chit funds and merchant banks. Ireland and Germany are respectively second and third for starting micro financing activities toRead MoreCoca-Colas Principles of Budgeting955 Words   |  4 Pagesin an innovative and different way that would make them stand out and less pressured to invest large costs into promoting themselves. One of its innovations is with its experimentations with food service, such s Coca-Cola Freestyle, where using micro-dosing technology, the hyper-technological soda fountain serves up 125 different flavors of soft drinks, flavored waters, sports drinks and lemonades and sends usage data, such as what flavors are most popular at what times of the day, to Coca-ColaRead MoreCauses And Policies Of Financial Crises1701 Words   |  7 Pagesdetermines the strength of the financial industry, and will aid policy makers to understand an upcoming credit boom. The two different types of postures are: hedge finance that provides more robust and low risk credits, while Ponzi finance is more risked averse. In periods of economic stability like the Great Moderation Ponzi finance tends to be more prevalent, potentially leading to the financial system’s fragility (Knell 2012). Secondly, financial liberalization fosters financial innovation amongRead MoreEbay Bids for Structured Change Essay e xample1300 Words   |  6 Pagesorganizational goals, and it is difficult for the organization to monitor the performance of individual managers in the functional areas (edugov). The addition of more buyout companies (PayPal, Skype) created an evolution in management design for eBay. The CEO and stockholders still needed to micro manage the company, so the new sub divisions were brought in and this created a change in the U form style was implemented. This new style then evolved into a better structure for faster decision making and

Tuesday, May 5, 2020

Waste Water Problems and Solutions in Bahrain free essay sample

Waste water In the Arab world the water challenges are well studied and researched. There are facts that water security is disappearing. Especially in Bahrain, where it is a small island and the demand of water is increasing year by year. Waste water in Bahrain started to occur by human activities of companies, agriculture and can include a wide range of pollution. Water is an important thing, therefore solutions should be made and to be delivered to the citizens of the importance of water nowadays.There is a limited awareness of Bahraini citizens about water limitations, they are using it without any concentrations or thinking. Lots of percentages water being used incorrectly whether in plantings, home usage, or other water based activities. This has caused many issues relating to water, even to the citizens of Bahrain because water is a necessity object in everything.Moreover, issues of water quality and maintenance are decisively important; as having a constant water supply besides the water resources it could affect the development of the country as well (Gulf News, 2010). We will write a custom essay sample on Waste Water Problems and Solutions in Bahrain or any similar topic specifically for you Do Not WasteYour Time HIRE WRITER Only 13.90 / page Water comes into mostly everything in life, it is important for human being and animals to live, plant protection where lots of agricultural industries and farming areas are being developed in the region. As well as, it’s involved in lots of manufacturing, chemicals and business sectors fields. As a fact it is more important than the oil which Bahrain is relying on for its economic aspects. Bahrain is planning new waste water treatment for the Tubli Sewage Treatment Plant. Khalifa Ebrahim Al Mansoor, the ministry assistant undersecretary stated in his report that the proposal of arranging a connection with the private sector in order to expand and upgrade the Tubli Sewage Treatment Plant will be positively expected at the end of year 2011.In addition, he also said that Tubli plant is not proficient with treating the problems related to waste water and Muharraq plant will pact the waste water and generate enough amount of water for landscaping. And as a result of that it will decrease the shortages of water in Bahrain. This privatization project is mainly developed to increase the Greenfield sewage plant treatment with facilitating the designing, financing, testing and operating well water usage in the region.Furthermore, this project is supposed to establish and introduce t he main concept of waste water management throughout the people and overall firms of Bahrain and reduce number of operational problems that are faced now and find solutions within the next 50 years (Clean Middle East, 2011). Only the stated above will not be enough for now, as people are not very much aware of the shortages that Bahrain is facing for water. That is why institutes and more awareness programs should be provided in the country in order to be able to succeed in reducing waste water problems.

Monday, April 6, 2020

An Introduction to Hypothesis Testing

An Introduction to Hypothesis Testing Hypothesis testing is a topic at the heart of statistics. This technique belongs to a realm known as inferential statistics. Researchers from all sorts of different areas, such as psychology, marketing, and medicine, formulate hypotheses or claims about a population being studied. The ultimate goal of the research is to determine the validity of these claims. Carefully designed statistical experiments obtain sample data from the population. The data is in turn used to test the accuracy of a hypothesis concerning a population. The Rare Event Rule Hypothesis tests are based upon the field of mathematics known as probability. Probability gives us a way to quantify how likely it is for an event to occur. The underlying assumption for all inferential statistics deals with rare events, which is why probability is used so extensively. The rare event rule states that if an assumption is made and the probability of a certain observed event is very small, then the assumption is most likely incorrect. The basic idea here is that we test a claim by distinguishing between two different things: An event that easily occurs by chance.An event that is highly unlikely to occur by chance. If a highly unlikely event occurs, then we explain this by stating that a rare event really did take place, or that the assumption we started with was not true. Prognosticators and Probability As an example to intuitively grasp the ideas behind hypothesis testing, we’ll consider the following story. It’s a beautiful day outside so you decided to go on a walk. While you are walking you are confronted by a mysterious stranger. â€Å"Do not be alarmed,† he says, â€Å"this is your lucky day. I am a seer of seers and a prognosticator of prognosticators. I can predict the future, and do it with greater accuracy than anyone else. In fact, 95% of the time I’m right. For a mere $1000, I will give you the winning lottery ticket numbers for the next ten weeks. You‘ll be almost sure of winning once, and probably several times.† This sounds too good to be true, but you are intrigued. â€Å"Prove it,† you reply. â€Å"Show me that you really can predict the future, then I’ll consider your offer.† â€Å"Of course. I can‘t give you any winning lottery numbers for free though. But I will show you my powers as follows. In this sealed envelope is a sheet of paper numbered 1 through 100, with heads or tails written after each of them. When you go home, flip a coin 100 times and record the results in the order that you get them. Then open the envelope and compare the two lists. My list will accurately match at least 95 of your coin tosses.† You take the envelope with a skeptical look. â€Å"I will be here tomorrow at this same time if you decide to take me up on my offer.† As you walk back home, you assume that the stranger has thought up a creative way to con people out of their money. Nevertheless, when you get back home, you flip a coin and write down which tosses give you heads, and which ones are tails. Then you open the envelope and compare the two lists. If the lists only match in 49 places, you would conclude that the stranger is at best deluded and at worse conducting some sort of scam. After all, chance alone would result in being correct about one half of the time. If this is the case, you would probably change your walking route for a few weeks. On the other hand, what if the lists matched 96 times? The likelihood of this occurring by chance is extremely small. Due to the fact that predicting 96 of 100 coin tosses is exceptionally improbable, you conclude that your assumption about the stranger was incorrect and he can indeed predict the future. The Formal Procedure This example illustrates the idea behind hypothesis testing and is a good introduction to further study. The exact procedure requires specialized terminology and a step by step procedure, but the thinking is the same. The rare event rule provides the ammunition to reject one hypothesis and accept an alternate one.

Monday, March 9, 2020

Theme - Definition and Examples in Composition

Theme s in Composition Definitions (1) In literature and composition, a  theme is the main idea of a text, expressed directly or indirectly. Adjective: thematic. (2) In composition studies, a theme is a short essay or  composition assigned as a writing exercise. See also: Composing My First College Essay, by Sandy KlemFive-Paragraph EssayModels of CompositionTheme WritingWhats Wrong With the Five-Paragraph Essay? See Examples and Observations below. Also, see: EpiphanyMotifPlotThesis Etymology From the Greek, placed or laid down Examples and Observations (definition #1): Simply put, a storys theme is its idea or point (formulated as a generalization). The theme of a fable is its moral; the theme of a parable is its teaching; the theme of a short story is its implied view of life and conduct. Unlike the fable and parable, however, most fiction is not designed primarily to teach or preach. Its theme, thus, is more obliquely presented. In fact, theme in fiction is rarely presented at all; readers abstract it from the details of characters and action that compose the story.(Robert DiYanni, Literature. McGraw-Hill, 2002) Orwells Theme(s) in the Essay A Hanging- A Hanging is [George] Orwells first distinctive work. It gives an apparently objective account of a ritualistic executionfrom fixed bayonets to a bag over the head of the condemnedin which the narrator officially and actively participates. . . . At this halfway point Orwell states his theme: till that moment I had never realized what it means to destroy a healthy, conscious man. When I saw the pris oner step aside to avoid the puddle, I saw the mystery, the unspeakable wrongness, of cutting a life short when it is in full tide. Instead of invoking religion, he asserts a quasi-religious sense of lifes sacrednessthe first expression of the instinctive humanism that characterizes all his work.(Jeffrey Meyers, Orwell: Wintry Conscience of a Generation. Norton, 2000)- A variation on this theme occurs in several of Orwells most famous texts containing epiphanies, moments of illumination in which the humanity of people he has hitherto viewed in terms of dehumanizing generalizations suddenly breaks through, and Orwells perception is jarred as he understands, with a shock, that these are people like himself. . . . In the early sketch entitled A Hanging (1931), Orwell describes how his idea of what it means to kill a man is altered by the Hindu prisoners gesture of stepping aside to avoid a puddle on the way to the gallows. What the text reveals, however, is that the prisoner at first l ooks to Orwell like a mere insignificant object. Into this scene, well defined in terms of the prisoners already marginal existence, breaks the unexpected gesture, making Orwell (or the Orwellian narrative persona) realize that the prisoner is alive, just as he is . . . . This chronicle is generally interpreted along the lines Orwell lays down, as the revelation of the barbarity of execution, but its primary meaning, I believe, is another. An inferiorized human being has for an instant become a genuine person in the eyes of one of the masters.(Daphne Patai,The Orwell Mystique: A Study in Male Ideology. University of Massachusetts Press, 1984) The Themes of the Novel Charlottes Web- Themes are subject to readers interpretation, so different individuals may identify different themes in the same book; the dominant idea or theme, however, should be apparent to readers.Charlottes Web offers many layers of meaning to readers. Younger children are apt to understand this book as an animal fantasy. Older children are ready to apprehend the cycle of life and death, while adults recognize the irony in a situation that gives one character credit for the creativity of another. This is why we recommend using Charlottes Web in the third or fourth grade, when children are ready to understand its major theme.(Barbara Stoodt et al., Childrens Literature:Discovery for a Lifetime. Macmillan, 1996)- Identifying theme is typically a bit more difficult perhaps because theme is often confused with plot summary or motif. . . . Charlottes Web (White, 1952) is a story about a pig whose life is saved by a spider is not a theme statement! It is a pl ot statement. Charlottes Web is a story about friendship is also not a theme statement! Rather, it is a statement identifying one of the most important motifs in the storyfriendship. A theme in Charlottes Web is that true friendship involves responsibilities as well as privileges is a theme statement!(R. Craig Roney, The Story Performance Handbook. Lawrence Erlbaum, 2001)- Besides mortality itself, throughout many idyllic scenes [in Charlottes Web] Andy [White] dabbed colorful spots of melancholy. He translated the song sparrows aria as sweet, sweet, sweet interlude and informed the reader that it referred to lifes brevity. Crickets harped on the same theme. But overall Andys theme was the joy of being alive, of reveling in the moment with visceral attention. What seemed like two themes were really one.(Michael Sims, The Story of Charlottes Web. Walker, 2011) The Difference Between Plot and ThemeIf you sometimes confuse plot with theme, keep the two elements separate by thinking of theme as what the story is about, and plot as the situation that brings it into focus. You might think of theme as the message of the storythe lesson to be learned, the question that is asked, or what it is the author is trying to tell us about life and the human condition. Plot is the action by which this truth will be demonstrated.(Phyllis Reynolds Naylor, quoted by Kenneth John Atchity and Chi-Li Wong in Writing Treatments That Sell, rev. ed. Henry Holt, 2003) Thesis and ThemeThe thesis is the main point you are trying to argue [in a composition]: for instance, that abortion is every womans right or that housing discrimination is wrong. The theme, on the other hand, is a motif established by orchestrated connotative language that reinforces the thesis. Theme differs from thesis in that theme relies on inference and suggested meaning rather than on direct st atement.(Kristin R. Woolever, About Writing: A Rhetoric for Advanced Writers. Wadsworth, 1991) Pronunciation: THEEM

Friday, February 21, 2020

Critically evaluate the current methods of high-throughput expression Essay

Critically evaluate the current methods of high-throughput expression profiling in normal and disease states - Essay Example These studies have provided information that was challenging to find, making it easy to detect diseases very early and applying the necessary intervention and treatment procedures on time reducing rates of morbidity and mortality. The first step n the quest to understand the cell function would be understanding gene expression of the various cells of the body. In that case, it would be easier to determine when cells are not expressed as expected. Scientists and researchers point out that gene expression anomalies mostly involve the Messenger RNA (mRNA). DNA Microarrays are used to measure the expression of cells within a predefined mRNA. Different cells are expected to be expressed in a certain way in the mRNA. Changes in expression include over-expression or under-expression. For example, scientists have confirmed that breast cancer cells express more mRNA for the membrane receptor (Suter, Babiss and Wheeldon, 2004). DNA methylation which is important in the normal DNA function and gene expression can be used to detect the changes in the DNA leading to abnormal expression and disease. Hyper-methylation and hypo-methylation have been associated with significant changes in some cells. Cells of the breast canter are usually hyper-methylated leading to neuroblastoma risks and response to the tamoxifen (Widschwendter et al., 2004; Martens et al., 2005). Hyper methylation has also been associated with Leukemia, Ovarian cancer and colorectal cancer (Baylin, 2005). The varying magnitudes of methylation in the cells are associated with different stages of cancer development, and DNA methylation technique can be used to determine the exact stage (Costello et al, 2000). Use of DNA and genes is made very easy by the availability of data of all genomes in the human body. Researchers can access this information anytime from the human genome project databases. Use of gene expression is a three step process that involves class comparison, class prediction and analyzing the va rious genes sets profiles. All this information is presented on pre-processed images which are normalized to make sense (Tarca et al, 2006). DNA microarrays are limiting in that they can only be used for know cells. This limitation necessitated the introduction of RNA sequencing in which unknown genes expression can be studied (Cloonan et al, 2008). Single cell sequencing in which the different types of healthy and cancerous cells can be sequenced individually has improved the effectiveness of DNA micro array studies. All the cells that are studies are amplified using the polymerase chain reaction (PCR) to achieve better and accurate results (Wang and Bodovitz, 2010). Micro arrays can be used to analyze thousands of cells from different patients at once making it time efficient unlike the previous methods of analysis. The technique provides information on DNA, RNA and the proteins simultaneously. Throughput profiling can also be done at the product level of gene expression; proteins in this case are studied for any anomalies. Mass Spectrometry is used to determine the differences between normal cells and diseased cells for example cancer cells (Aebersold and Mann, 2003). This procedure has proved very important in detecting prostate cancer in early stages, which has been a major challenge. In this case, the fluids, peptides and serum from the prostate are examined using the SELDI mass spectrometer which uses affinity capture. Some cells are